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San Diego is home to one of the largest biotech clusters in the nation, and there are a number of universities in the city that offer pharmaceutical and biotech-related degree programs.
The American automotive industry has suffered a long, slow decline since its heyday in the mid-1950s. The Big Three - General Motors, Ford and Chrysler - have nearly been overtaken by the Big One, namely Toyota.
In his 1901 book Cyclopedia of American Horticulture, Liberty Hyde Bailey, one of America's most important botanists and co-founder of the American Society for Horticultural Science, defined with these words the discipline he had helped to pioneer: